Multiparametric MRI-Targeted TRUS Prostate Biopsies Using Visual Registration

Multiparametric MRI-Targeted TRUS Prostate Biopsies Using Visual Registration

Prebiopsy multiparametric prostate MRI (mp-MRI), followed by transrectal ultrasound-guided (TRUS-G) target biopsies (TB) of the prostate is a key combination for the diagnosis of clinically significant prostate cancers (CSPCa), to avoid prostate cancer (PCa) overtreatment. Several techniques are available for guiding TB to the suspicious mp-MRI targets, but the simplest, cheapest, and easiest t...

Non-rigid MRI-TRUS registration in targeted prostate biopsy

A non-rigid registration method is presented for the alignment of pre-procedural magnetic resonance (MR) images with delineated suspicious regions to intra-procedural 3D transrectal ultrasound (TRUS) images in TRUSguided prostate biopsy. In the first step, 3D MR and TRUS images are aligned rigidly using six pairs of manually identified approximate matching points on the boundary of the prostate...

Validation of MRI to TRUS registration for HDR prostate brachytherapy Running head title: MRI to TRUS registration for prostate brachytherapy

Evaluation of Inter-session 3D-TRUS to 3D-TRUS Image Registration for Repeat Prostate Biopsies

To ensure accurate targeting and repeatability, 3D TRUS-guided biopsies require registration to determine coordinate transformations to (1) incorporate pre-procedure biopsy plans and (2) compensate for inter-session prostate motion and deformation between repeat biopsy sessions. We evaluated prostate surface- and image-based 3D-to-3D TRUS registration by measuring the TRE of manually marked, co...

Association of multiparametric MRI quantitative imaging features with prostate cancer gene expression in MRI-targeted prostate biopsies

Standard clinicopathological variables are inadequate for optimal management of prostate cancer patients. While genomic classifiers have improved patient risk classification, the multifocality and heterogeneity of prostate cancer can confound pre-treatment assessment. The objective was to investigate the association of multiparametric (mp)MRI quantitative features with prostate cancer risk gene...